Using biology to convert low-cost sugar to high-value chemicals.


Four Years and Counting

Founded in 2010, we set out to provide innovative microbial solutions for today’s renewable chemical challenges. We engineer microbes to consume sugars and produce chemicals, targeting compounds where biological production is inherently cost-advantaged over petrochemical production.

Optimized Metabolic Pathways

We excel at engineering microbes. Using high-throughput strain engineering techniques, we are able to quickly move from proof-of-concept demonstrations to commercial production processes. Our work has been supported, in part, by over $5.75MM in federal grants from the U.S. Department of Energy, U.S. Department of Agriculture, and National Science Foundation.

Our Products

Lygos' First Product: Malonic Acid

Lygos’ first product, malonic acid, is a high-value specialty chemical today. Existing routes for its production are costly and hazardous, requiring sodium cyanide and chlorine. Lygos’ technology is based on low-cost fermentation of sugar to malonic acid, enabling development of new applications for this versatile chemical.


Scaling up For Greater Advances

Our malonic acid technology is currently at pilot plant scale. We are optimizing the production processes for our second and third products, and aim to begin scaling these processes within the next year.

Lawrence Berkeley Nat'l Lab - Roy Kaltschmidt, photographer